GPCRIPDB: Pairwise Alignments

   2005, GPCRIPDB.


The pairwise alignment has been generated with the "genewise" program of the Wise2 package. The output shows the protein sequence on the first line, followed by a line indicating the similarity level of the match, followed by 4 lines representing the DNA sequence; The DNA sequence descending in triplets, each triplet being a codon. The translation of each codon is shown above it.
Between the two protein sequences a line indicating the similarity of the match is printed. "+" indicates a conservative mismatch while "- "indicates a dramatic one. Mismatches are indicated by "***" in the left column in addition to "!" at the relevant position(s).


genewise $Name: wise2-2-0 $ (unreleased release)
This program is freely distributed under a GPL. See source directory
Copyright (c) GRL limited: portions of the code are from separate copyright

Query protein:       GPA10_CAEEL
Comp Matrix:         blosum62.bla
Gap open:            12
Gap extension:       2
Start/End            default
Target Sequence      CEC55H1_5
Strand:              forward
Start/End (protein)  default
Gene Paras:          human.gf
Codon Table:         codon.table
Subs error:          1e-05
Indel error:         1e-05
Model splice?        model
Model codon bias?    flat
Model intron bias?   tied
Null model           syn
Algorithm            623

genewise output
Score 882.18 bits over entire alignment
Scores as bits over a synchronous coding model

Warning: The bits scores is not probablistically correct for single seqs
See WWW help for more info.

GPA10_CAEEL        1 MGVCQSFVLTDEMKDQIKVNKEIEKQLEKKKNMQLEQTVLLLGPGESGK 
                     MGVCQSFVLTDEMKDQIKVNKEIEKQLEKKKNMQLEQTVLLLGPGESGK 
                     MGVCQSFVLTDEMKDQIKVNKEIEKQLEKKKNMQLEQTVLLLGPGESGK 
CEC55H1_5          1 aggtcttgcaggaagcaagaagagaccgaaaaactgcagcccgcggaga 
                     tgtgactttcaataaatataaataaataaaaatataacttttgcgagga 
                     ggctgatactcgggtgcatcaaaaagcaggacgaggacttaggttataa 


GPA10_CAEEL       50 STVMKQMRAMTGNYTKTELHERKVLIIQNLCQFSEMLLEYVREYILEMT 
                     STVMKQMRAMTGNYTKTELHERKVLIIQNLCQFSEMLLEYVREYILEMT 
                     STVMKQMRAMTGNYTKTELHERKVLIIQNLCQFSEMLLEYVREYILEMT 
CEC55H1_5        148 aagaacaagaagataaagccgcagcaacattcttgattgtgagtatgaa 
                     gcttaatgctcgaacacataagattttaatgatcatttaatgaattatc 
                     ttcgaggacgtaccagaaacaaagatagtatattgggaaccaattgggg 


GPA10_CAEEL       99 EDDDKRYTVMCEELKMAVIHDGIMRPELADTLKEFWGNSAIQDAYSKRD 
                     EDDDKRYTVMCEELKMAVIHDGIMRPELADTLKEFWGNSAIQDAYSKRD 
                     EDDDKRYTVMCEELKMAVIHDGIMRPELADTLKEFWGNSAIQDAYSKRD 
CEC55H1_5        295 ggggactagatggcaaggacggaaacgcggacagttgaagacggttaag 
                     aaaaagacttgaatatcttaagttgcatcactaatggagctaacacaga 
                     acttaattggcaagaggatttaagatacctaggacgactaagcgtcgac 


GPA10_CAEEL      148 TFHLTDSAKYFFDNIDRIKLPGFEPTNQDIVHIRVPTTGVAQVEVIMNN 
                     TFHLTDSAKYFFDNIDRIKLPGFEPTNQDIVHIRVPTTGVAQVEVIMNN 
                     TFHLTDSAKYFFDNIDRIKLPGFEPTNQDIVHIRVPTTGVAQVEVIMNN 
CEC55H1_5        442 atctagagatttgaagcaatcgtgcaacgagcacgcaagggcgggaaaa 
                     ctatcagcaattaatagtatcgtaccaaattatgtcccgtcatatttaa 
                     attgattcgtcccccctaagactagatgtttcagatagataacattgct 


GPA10_CAEEL      197 IKLMICDCGGQRSERRKWYHFFDEADAVLFVAAISEFDQKLAEDEETNR 
                     IKLMICDCGGQRSERRKWYHFFDEADAVLFVAAISEFDQKLAEDEETNR 
                     IKLMICDCGGQRSERRKWYHFFDEADAVLFVAAISEFDQKLAEDEETNR 
CEC55H1_5        589 aataatgtggcctgacattcttggggggctgggaagtgcatgggggaac 
                     tatttgagggagcaggagaattaacacttttcctgataaatcaaaacag 
                     caggtctttaaataaaagtctctgtcttttagttcgttggaggtaggct 


GPA10_CAEEL      246 MHESIRLFWTVFNGKFFKKAAVILFLNKIDLFEEKVKHVKIKDYFPKFE 
                     MHESIRLFWTVFNGKFFKKAAVILFLNKIDLFEEKVKHVKIKDYFPKFE 
                     MHESIRLFWTVFNGKFFKKAAVILFLNKIDLFEEKVKHVKIKDYFPKFE 
CEC55H1_5        736 acgtaatttagtagattaagggactcaaagttggagacgaaagttcatg 
                     taactgttgcttagattaacctttttaatattaaataatataaatcata 
                     gtaccagcgatttagtcaagacatcgcattgcggaaatggtgtctaata 


GPA10_CAEEL      295 GANTVSEGTKFFRRQFREGIHPDFKKRMYTHETCAISDQVQIIINTVID 
                     GANTVSEGTKFFRRQFREGIHPDFKKRMYTHETCAISDQVQIIINTVID 
                     GANTVSEGTKFFRRQFREGIHPDFKKRMYTHETCAISDQVQIIINTVID 
CEC55H1_5        883 ggaagtggaattcactaggaccgtaaaatacgatgatgcgcaaaaagag 
                     gcactcagcattggatgagtacataagtacaacgctcaatatttactta 
                     aacataatagctgaataagtcgccaaagcctaataagtataacctagat 


GPA10_CAEEL      344 TVIQDNLKDTGMI                                     
                     TVIQDNLKDTGMI                                     
                     TVIQDNLKDTGMI                                     
CEC55H1_5       1030 agacgacagagaa                                     
                     cttaaataacgtt                                     
                     attattcatgaga                                     


//


Button bar
F.Horn (gpcrdbcmbi.kun.nl), 24-May-2005