Functional and binding data for rat muscarinic cholinergic receptor

• List of ligands
• List of receptors

Ligand	pKi value		Method	Comment
1,3,4,6,11,11a-hexahydro-2H-pyrazino[1,2-b]isoquinoline	4.5		1-01801
1-(2-pyridinyl)piperazine(E)-2-buenedioate (1:1) salt	4.8		1-01801
1-(6-chloro-2-pyridinyl)piperazine(E)-2-butenedioate (1:1) salt	5.3		1-01801
1-[2-(methylthio)phenyl]piperazine(Z)-2-butenedioate (1:1) salt	6.1		1-01801
2'-methylspiro[1-azabicyclo[2.2.2.]octane -3,5'-[1,3]oxathiolane]monohydrochloride	5.8		1-01801
3-[2-(trifluoromethyl)phenoxyl]-1- azabicyclo[2.2.2.]octane ethanedioate (R)	6.7		1-01801
3-[2-(trifluoromethyl)phenoxyl]-1- azabicyclo[2.2.2.]octane ethanedioate (R)	6.8		1-01801
3-[2-(trifluoromethyl)phenoxyl]-1- azabicyclo[2.2.2.]octane ethanedioate (R)	7.1		1-01801
3-(4-chloro-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridineoxalate	7.5		1-01801
3-(4-hexyloxy-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridine(Z)-2-butenedioate (1:1) salt	8		1-01801
3-[4-(hexylthio)-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridine(Z)-2-butenedioate	7.9		1-01801
4-[2-[(4-fluorophenyl)methoxy]ethyl]-1-(phenylmethyl) piperidine(E)-2-butenedioate (1:1)	8		1-01801
4-damp bromide	8.2		1-01801
4-damp bromide	8.2		1-01801
4-damp bromide	8.4		1-01801
4Cl-McN-a343	5.3		1-01801
5-(4-chlorophenyl)-2,3,5,6-tetrahydroimidazol [1,2-c]quinazoline	6.4		1-01801
AF-102b/fks-508	5.6		1-01801
AF-30	5.3		1-01801
AF-30	5.3		1-01801
AF-DX 116 bs	7.1		1-01801
AH 6405	5.1		1-01801
AH 6405	5.1		1-01801
AH 6405	5.5		1-01801
AH 6405	<5.3		1-01801
AHR 602	4.6		1-01801
AHR 602	5.4		1-01801
AHR 602	5		1-01801
AHR 602	<5.3		1-01801
AHR 603	<6.3		1-01801
McN-5707	7.2		1-01801
RS 86 HBr	5.2		1-01801
RS 86 HBr	5.4		1-01801
RS 86 HBr	5.9		1-01801
UH-AH 37 HCl H2O	7.4		1-01801
UH-AH 37 HCl H2O	7.4		1-01801
YM796	5.8		1-01801
YM796	5.9		1-01801
YM796	6.2		1-01801
aceclidine HCl	5.4		1-01801
aceclidine HCl	5.4		1-01801
arecaidine propargyl ester HCl	7		1-01801
arecoline HBr	5.9		1-01801
arecoline HBr	6.2		1-01801
arecoline HBr	6.4		1-01801
benzetimide hydrochloride	8.9		1-01801
benzetimide hydrochloride	9.3		1-01801
benzetimide hydrochloride	9.5		1-01801
bethanechol chloride	4.3		1-01801
bethanechol chloride	5.1		1-01801
bethanechol chloride	5.1		1-01801
dexetimide hydrochloride	10.9		1-01801
dexetimide hydrochloride	10		1-01801
dexetimide hydrochloride	9.7		1-01801
dicyclomine HCl	7.4		1-01801
dicyclomine HCl	7.7		1-01801
dicyclomine HCl	8.2		1-01801
ethylcholine iodide (o-)	4.7		1-01801
isoarecoline HCl	4.7		1-01801
levetimide hydrochloride	5.8		1-01801
levetimide hydrochloride	5.9		1-01801
levetimide hydrochloride	6		1-01801
mianserin HCl (racemate)	6.5		1-01801
mianserin HCl (racemate)	6.5		1-01801
minaprine 2HCl	<4.9		1-01801
mirtazapine HCl (racemate)	6		1-01801
mirtazapine HCl (racemate)	6		1-01801
oxotremorine m	6.4		1-01801
quinuclidinyl benzilate	10.1		1-01801
quinuclidinyl benzilate	10		1-01801
quinuclidinyl benzilate	9.7		1-01801
secoverine HCl	8.6		1-01801
secoverine HCl	8.8		1-01801
secoverine HCl	9.1		1-01801
sertindole	6.9		1-01801
telenzepine diHCl	7.9		1-01801
telenzepine diHCl	8.2		1-01801
telenzepine diHCl	8.4		1-01801
threo-DL-3-hydroxyaspartic acid	<5.2		1-01801
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	5.97		1-01801