Functional and binding data for rat serotonin 5HT1A receptor

• List of ligands
• List of receptors

Ligand	pKi value		Method	Comment
1,3,4,6,11,11a-hexahydro-2H-pyrazino[1,2-b]isoquinoline	4.9		1-02301
1-(2-pyridinyl)piperazine(E)-2-buenedioate (1:1) salt	6.2		1-02301
1-(3-methoxyphenyl)piperazine (Z)-2-butenedioate (1:1)	6.3		1-02301
1-(3-methoxyphenyl)piperazine (Z)-2-butenedioate (1:1)	>5.1		1-02301
1-(4-methoxyphenyl)piperazine dihydrochloride	<5.1		1-02301
1-(6-chloro-2-pyridinyl)piperazine(E)-2-butenedioate (1:1) salt	6.6		1-02301
1-[2-(methylthio)phenyl]piperazine(Z)-2-butenedioate (1:1) salt	7.8		1-02301
2'-methylspiro[1-azabicyclo[2.2.2.]octane -3,5'-[1,3]oxathiolane]monohydrochloride	4.6		1-02301
2-methyl-1-[1-[3-(5-pyrimidinyl)phenyl]butyl] -1H-benzimidazole(E)-2-butenedioate	<5.7		1-02301
3-[2-(trifluoromethyl)phenoxyl]-1- azabicyclo[2.2.2.]octane ethanedioate (R)	<5.7		1-02301
3-(4-chloro-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridineoxalate	5.4		1-02301
3-(4-hexyloxy-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridine(Z)-2-butenedioate (1:1) salt	7		1-02301
3-[4-(hexylthio)-1,2,5-thiadiazol-3-yl) -1,2,5,6-tetrahydro-1-methylpyridine(Z)-2-butenedioate	5.5		1-02301
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl) benzonitrile monohydrochloride	<5.1		1-02301
4-[2-[(4-fluorophenyl)methoxy]ethyl]-1-(phenylmethyl) piperidine(E)-2-butenedioate (1:1)	5		1-02301
5-(4-chlorophenyl)-2,3,5,6-tetrahydroimidazol [1,2-c]quinazoline	4.9		1-02301
8-chloro-2,3,4,5-tetrahydro-5-phenyl -1H-3-benzazepin-7-olhydrochloride (S)	5.9		1-02301
8-OH DPAT	10.4		1-02301
8-OH DPAT	9.2		1-02301
8-OH DPAT	9.2		1-02301
8-OH DPAT	9.8		1-02301
CGS 12066b	7.6		1-02301
DOI (R-)	5.1		1-02301
DOI (racemate)	4.4		1-02301
DOI (racemate)	5.2		1-02301
DOI (racemate)	<3.5		1-02301
LPA	<5.6		1-02301
MCPP	6.5		1-02301
MCPP	6.5		1-02301
MCPP	6.6		1-02301
MK 212 HCl	5.5		1-02301
MK 212 HCl	5.5		1-02301
MK 212 HCl	5.7		1-02301
MK 212 HCl	6		1-02301
McN-5707	5.5		1-02301
N-[2-(3,4-dimethoxyphenyl)ethyl]-N-methyl-N'- [2-[(phenylmethyl)thio]phenyl]-1,2-ethanediamine	>5.5		1-02301
OMPP	7.2		1-02301
OMPP	>5.6		1-02301
RU 24969	8.4		1-02301
RU 24969	8.5		1-02301
RU 24969	8.7		1-02301
RU 24969	8.8		1-02301
RU 38486	<5.6		1-02301
SCH-23390 maleate	6.5		1-02301
TFMPP	6.8		1-02301
TFMPP	6.9		1-02301
TFMPP	6.9		1-02301
TFMPP	7.2		1-02301
UH-301	7.5		1-02301
UH-301	7.5		1-02301
UH-301	7.6		1-02301
bromerguride	8.2		1-02301
bufotemine monooxalate monohydrate	8.6		1-02301
bufotemine monooxalate monohydrate	8.7		1-02301
bufotemine monooxalate monohydrate	>8.9		1-02301
buspirone HCl	8		1-02301
buspirone HCl	9.7		1-02301
buspirone HCl	>10.9		1-02301
cericlamine HCl	<4.4		1-02301
eltoprazine	7.7		1-02301
ergonovine hydrogen maleate	8		1-02301
flumexedol (cerm 1841)	7.1		1-02301
flumexodol (+)	7.5		1-02301
flumexodol (-)	6.1		1-02301
gepirone .HCl	7.1		1-02301
gepirone .HCl	7.4		1-02301
gepirone .HCl	7.4		1-02301
idazoxan	6.7		1-02301
ipsapirone	10		1-02301
ipsapirone	8.1		1-02301
ipsapirone	9.1		1-02301
ipsapirone	>9.1		1-02301
lisuride hydrogen maleate	8.6		1-02301
lisuride hydrogen maleate	8.6		1-02301
lisuride hydrogen maleate	8.6		1-02301
lisuride hydrogen maleate	>8.8		1-02301
mdl72832 a-4	9.1		1-02301
mebicar	<5.7		1-02301
mescaline hydrochloride	<4.6		1-02301
mesulergine	6.2		1-02301
mesulergine	6.3		1-02301
mesulergine	6.3		1-02301
mianserin HCl (racemate)	5.9		1-02301
mianserin HCl (racemate)	6.1		1-02301
mianserin HCl (racemate)	6.2		1-02301
mianserin HCl (racemate)	6		1-02301
mianserin HCl (racemate)	6		1-02301
mianserin HCl R(-)	6.5		1-02301
mianserin HCl S(+)	6.4		1-02301
mirtazapine HCl (racemate)	4.9		1-02301
mirtazapine HCl (racemate)	4.9		1-02301
mirtazapine HCl (racemate)	5.3		1-02301
mirtazapine HCl (racemate)	5.3		1-02301
mirtazapine HCl (racemate)	5.4		1-02301
mirtazapine HCl (racemate)	5.4		1-02301
mirtazapine HCl R(-)	4.8		1-02301
mirtazapine HCl R(-)	4.9		1-02301
mirtazapine HCl R(-)	5.1		1-02301
mirtazapine HCl S(+)	5.1		1-02301
mirtazapine HCl S(+)	5.2		1-02301
mirtazapine HCl S(+)	5.4		1-02301
mirtazapine HCl S(+)	5.8		1-02301
phendimetrazine	<4.4		1-02301
pindolol	7.7		1-02301
pindolol	7.8		1-02301
pindolol	7.9		1-02301
pindolol	8		1-02301
pirenpirone	5.6		1-02301
pirenpirone	5.6		1-02301
pirenpirone	5.7		1-02301
propylnorapomorphine HCl (N-)	6.2		1-02301
quipazine maleate	5.3		1-02301
quipazine maleate	5.4		1-02301
quipazine maleate	5.8		1-02301
rauwolscine HCl	7.5		1-02301
rauwolscine HCl	7.6		1-02301
rauwolscine HCl	7.7		1-02301
risperidone	6.1		1-02301
ritanserin	5.7		1-02301
ritanserin	5.8		1-02301
ritanserin	5.9		1-02301
sertindole	5.9		1-02301
sertraline HCl	<5.1		1-02301	BINDING AT 1.0E-09M WAS TAKEN AS TOTAL BINDING
spiperone	6.8		1-02301
spiperone	6.9		1-02301
spiperone	7.1		1-02301
spiroxatrine	8.5		1-02301
spiroxatrine	8.5		1-02301
spiroxatrine	8.6		1-02301
sumatriptan	6.1		1-02301
sumatriptan	6.4		1-02301
sumatriptan	6.6		1-02301
sumatriptan	6.6		1-02301
threo-DL-3-hydroxyaspartic acid	4.9		1-02301
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	7.4		1-02301
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	7.5		1-02301
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	7.6		1-02301
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	8.9		1-02301
trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl- 1H-dibenz(2,3:6,7)oxepino(4,5-c)pyrrole maleate	8		1-02301
trifluperidol HCl	6.2		1-02301
umespirone	7.5		1-02301
venlafaxine	4.8		1-02301
vuf 9147	>5.7		1-02301
vuf 9148	>5.7		1-02301
way-100135	7.8		1-02301
xylamidine tosylate	<5.1		1-02301
zolpidem	5.2		1-02301