Functional and binding data for human serotonin 5HT1A receptor

Copyright (C) 2002, GPCRDB.

List of ligands
List of receptors

Ligand pK_i value Method Comment
8-OH DPAT 8.2 2-01801

8-OH DPAT 8.2 2-01801

8-OH DPAT 8.4 2-01801

8-OH DPAT 8.5 2-01801

8-OH DPAT 8.5 2-01801

8-OH DPAT 8.8 2-01801

8-OH DPAT 9.1 2-01801

8-OH DPAT 9.1 2-01801

8-OH DPAT 9.4 2-01801

8-OH DPAT 9.4 2-01801

8-OH DPAT >8 2-01801

MCPP 6.8 2-01801

MCPP 7.5 2-01801

MCPP 7.5 2-01801

MCPP 7 2-01801

MCPP 7 2-01801

TFMPP 6.7 2-01801

TFMPP 6.8 2-01801

TFMPP 6.8 2-01801

TFMPP 6.9 2-01801

TFMPP 6.9 2-01801

buspirone HCl 7.7 2-01801

buspirone HCl 7.7 2-01801

buspirone HCl 8.3 2-01801

buspirone HCl 8 2-01801

buspirone HCl 8 2-01801

ketanserin tartrate 5.9 2-01801

ketanserin tartrate 6.2 2-01801

mesulergine 5.9 2-01801

mesulergine 6.3 2-01801

mesulergine 6.6 2-01801

mesulergine 6.6 2-01801

mesulergine 6.9 2-01801

mesulergine 7 2-01801

mesulergine 7 2-01801

mianserin HCl (racemate) 6.3 2-01801

mianserin HCl (racemate) 6.3 2-01801

mianserin HCl (racemate) 6.6 2-01801

mianserin HCl (racemate) 6.6 2-01801

mianserin HCl (racemate) 6.6 2-01801

olanzapine 5.6 2-01801

olanzapine 5.9 2-01801

olanzapine 6 2-01801

olanzapine 6 2-01801

quipazine maleate 5 2-01801

quipazine maleate 6 2-01801

quipazine maleate 6 2-01801

quipazine maleate 6 2-01801

quipazine maleate 6 2-01801

remoxipride HCl H₂O 5.1 2-01801

remoxipride HCl H₂O 5.1 2-01801

remoxipride HCl H₂O 5.5 2-01801

remoxipride HCl H₂O 5.8 2-01801

risperidone 6.1 2-01801

risperidone 6.6 2-01801

ritanserin 6.9 2-01801

ritanserin 6.9 2-01801

ritanserin 6.9 2-01801

ritanserin 7 2-01801

ritanserin 7 2-01801

spiperone 7.4 2-01801

spiperone 7.6 2-01801

spiperone 7.6 2-01801

spiperone 7.6 2-01801

spiperone 7.6 2-01801

(C) GPCRDB. F.H., David Lutje Hulsik (D.LutjeHulsik@cmbi.kun.nl), 18-Mar-2002