Dear Colleagues,
There is considerable discussion as to the current state of GPCR modeling progress, particularly in terms of docking of agonists and antagonists, as well as how fine the experimental structural coverage is needed for more reliable modeling/docking experiments. We have therefore initiated a community assessment to evaluate the current status and uncover new areas of needed investigation and development in GPCR modeling and docking based on a recently determined structure. This assessment is similar in fashion to CASP and CAPRI which continue to be critically important in evaluating the progress on de novo protein structure and protein-protein predictions.
If you are interested in participating in this community project which we hope you will, please visit the website http://jcimpt.scripps.edu/GPCRDock/default.aspx. Information will be sent by August 25th, with models due September 25th, 2008.
Thank you for considering this opportunity and helping the scientific community evaluate where the field is at. Please forward this announcement on to any colleagues you think will be interested in participating.
Sincerely,
Charlie Brooks
Scott Dixon
John Moult
Raymond Stevens