Updates

A whole new interface based on Apache Wicket, allowing for a much more interactive user experience.
Detailed help for all aspects of the GPCRDB is available, indicated by this icon:

It works!

. Clicking it will open a popup window containing the help (try it!).
Use cases to show you how to perform the most common tasks have been added to our new usage page.
We have a FAQ! If you feel like stuff is missing, please let us know!
There is a statistics table on the contents page.
On the top-right part of every page there is a search field, allowing for fast searching for proteins (look at it's help for usage details).
Quite a few bugs were removed.
And loads of minor improvements ...

Due to (too) strict cutoffs in a large number of olfactory families a lot of olfactory receptors were missed in the previous release. We are happy to embrace them again.
We now use the NR database from the NCBI to mine GPCRs. This has resulted in a significant increase in receptors in the database.
The previous release contained somewhere around 6.000 proteins, while we now have about 20.000 receptors. (please look at the contents page for the exact numbers)

The were quite a few errors in the sequence GPCRDB-numbering (special numbers). A checking mechanism was created to assure that alignment positions conform to a list of reference residues/positions.

The mutant prediction server is now available. This tool can predict the effects of mutations in class A GPCRs.
We have built a custom alignment creator service . This allows you to create your own alignment by specifying the families you would like to align and applying certain filters. Detailed help is available.
You can now BLAST your sequences against the GPCRDB!

Version 8.10.6 of the GPCRDB is released.

This release is a major overhaul of the GPCRDB, rewriting everything from scratch. A large number of new profiles were created by Laerte Oliveira, which resulted in more families and proteins.

For update details from older releases, please visit this page

GPCRDB