About

Welcome to the GPCRDB (G Protein-Coupled Receptor Data Base) partnership and acknowledgement page.
First, read the legal notice.

The GPCRDB was started in the early 90's when Bob Bywater, Ad IJzerman, Friedrich Rippmann, and Gert Vriend organized a series of small GPCR workshops at the EMBL. Before the introduction of the first browsers, the GPCRDB worked as an automatic Email answering system that could send sequences, alignments, and homology models to the users. In 1994 the internet was firmly established in its present form, and money was obtained from the fourth EU framework to set up the GPCRDB. Florence Horn joined us to do this project. When she left us at the end of a four-year post-doc period the GPCRDB was firmly established as the prime source of information for GPCR data. And most of you will still recognize Figure 1. Flo left us to work with Fred Cohen. In his lab she wrote the MuteXt software that extracts mutant information from the literature. In this period she maintained the GPCRDB, and she kept doing that till a few weeks before her tragic death in 2006. Florence will for ever remain a member of the GPCRDB family.

In 2007 TIPharma offered us the possibility to revive the GPCRDB. Bas Vroling joined the team, and, as you can see, revived the GPCRDB. We would also like to thank NBIC for their support.

This page would not be complete without Laerte Oliveira. Ever since the start of the GPCRDB project Laerte has been our GPCR dictionary. He knows the literature, he knows all sequences by hearth, he is responsible for the alignments, and for a series of innovations. Laerte recently retired, but he is still our full-time adviser.

Many people have contributed over the years to the shape of the GPCRDB that you see now. Rob Hooft was, en Maarten Hekkelman now is our bit and byte guru. Maarten also wrote the profile BLAST. Fabien Campagne wrote the snake plot software for us. Margot Beukers, Fred Cohen, Oyvind Edvardsen, Kurt Kristiansen, have been involved in the mutant section of the GPCRDB; Oyvind and Kurt made tinyGRAP that now is integrated in the GPCRDB. Wilma Kuipers, Nora vd Wenden, Mike Singer, and Frank Kolakowsky were good colleagues and intellectual sparring partners that helped shape the GPCRDB in its early days. Lisa Holm, Karl Aberer, Amos Bairoch, Nigel Brown, Antonio Paiva, Thure Etzold, and Antoine Daruvar have over the last two decades all contributed to the GPCRDB.