GPCR-specific PDF reader

The GPCR-specific PDF reader allows you to enrich your scientific literature with information and knowledge from the GPCRDB. Relevant information for genes, proteins, residues and mutations is automatically retrieved from the GPCRDB and made available to you. This information is integrated with the article in a non-obtrusive way; it is only there where and when you want it. This software helps you put your literature in the context of the total body of knowledge related to GPCRs, providing you with instant access to current, integrated, validated, internally consistent data and information. Try it!

Downloads

For Mac OS X Start Download Mac OS X 10.5 (Leopard) and above supported (universal binary).

For Windows Start Download XP, Vista and Windows 7 supported.

For Linux Installation Instructions Ubuntu and Debian supported

Usage

• Once installed, usage is simple: From with Utopia Documents, open a PDF document, right click and select 'Annotate Document' - 'Annotate with GPCRDB'
• When the annotation is complete, you can highlight all concepts for which we have information available by pressing the space bar

• Clicking on the highlighted words will display relevant information in the sidebar:

Examples

The following papers are known to beautifully illustrate the possibilities of this software:

• Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor., Gao et al.
• Residues Val254, His256, and Phe259 of the Angiotensin II AT1 Receptor Are Not Involved in Ligand Binding but Participate in Signal Transduction., Han et al.
• Engineering the melanocortin-4 receptor to control constitutive and ligand-mediated G(S) signaling in vivo., Srinivasan et al.
• The crystallographic structure of the human adenosine A2A receptor in a high-affinity antagonist-bound state: implications for GPCR drug screening and design., Jaakola and IJzerman
• Structure and function of an irreversible agonist-��2 adrenoceptor complex., Rosenbaum et al.

but please do use your own PDFs! We highly appreciate any feedback, suggestions and bug reports!